Fifty four drummers created an avenue through which the Earl of Wessex, representing the Queen, and International Paralympic Committee chairman Sir Philip Craven entered the stadium.
They arrived in a custom-built car that began life as a military vehicle used in Afghanistan and was driven by Captain Tony Harris, who lost his left leg below the knee when he was caught in a blast in Sangin, Afghanistan in 2009.
Blind autistic singer Lissa Hermans, who also performed at the Queen's Diamond Jubilee this year, sang the National Anthem.
The spectacular and moving ceremony was another display of creativity and British eccentricity, and featured global megastars Coldplay.
Coldplay frontman Chris Martin said: "Being asked to play at the closing celebrations for the Paralympic athletes in London is such a great honour for us. It was one of the biggest nights of our lives and we were excited to try to create a performance for the last night of the games that closed London 2012 in style."