The campaign is part of a £30 million Scottish Government initiative which aims to increase the number of cases of cancer detected early by 25%.
Smith said: "For too many years women have been confused and scared about what to look for. This campaign should help inform people about some of the signs related to breast cancer and encourage them to seek help.
"I am proud that this campaign will help to educate and inform women and men because increased awareness will save lives. I lost my own mum to breast cancer and I know that if she had seen this campaign she would have known what she was looking for and perhaps visited the doctor and been checked much earlier."
Scotland's Health Secretary Nicola Sturgeon said the adverts take a "bold approach which has not been used before".
She said: "Women can often be confused about what to look for and it is important that we get the message across that it's not just lumps that can be a sign of breast cancer. I hope that this drive will get people talking about breast cancer and encourage people to become more aware of the signs and symptoms."